P1060: Phase II, parallel, randomized, clinical trials comparing the responses to initiation of NNRTI-based antiretroviral therapy in HIV-infected infants who have not previously received Single dose Nevirapine for prevention of Mother-to-child HIV transmission
Study Location:
India
Topic:
HIVMaternal-Child Health and HIV
Clinicaltrials.gov Link:
https://clinicaltrials.gov/ct2/show/NCT00307151?term=infants+single+dose+nevirapine&rank=2
IRB#:
NA_00013549
Coordinator:
Nishi Suryavanshi
Enrollment:
Closed
Trial Period:
Completed
A single dose of nevirapine (SD NVP) given to an HIV infected pregnant woman followed by a single dose to her infant has been shown to be an effective way of reducing the risk of mother-to-child transmission (MTCT) of HIV. The purpose of this study was to compare the effectiveness of a non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral regimen versus a protease inhibitor (PI)-based regimen in HIV infected infants who had or had not been exposed to SD NVP for prevention of MTCT.
HIV-infected infants and children ≥ 2 months to < 36 months of age who are eligible for ART as defined by the WHO pediatric algorithm